Particle Characterization For Biotherapeutics

Fully configured to support applications across protein, antibody, cell, and gene therapy workflows, Aura+ brings particle characterization to earlier stages of therapeutic development, so you can make better decisions sooner.

Aura plus intrument

Particle Identification


5 µL to 10 mL Volume


1 Minute Per Sample


High Magnification Imaging

Why Choose Aura+?

When you need the flexibility to conduct particle characterization analyses on different types of biologics, including protein and antibody therapeutics, cell therapies, and gene therapies, the Aura+ has got you covered.

Analyze small volumes. The minimum sample volume is just 5 µL, enabling particle characterization earlier in the development timeline when sample volumes can be limited.

Gain insight quickly. With a 96-well membrane plate and the ability to analyze one sample every minute, the Aura+ takes you from labeled samples to data in as little as 90 minutes.

Get Fast, Definitive Particle Identification With Three Fluorescence Channels

Aura+ comes with three fluorescence channels so you can get the same information from one experiment that would otherwise take three different studies.

In addition, Aura+ definitively identifies different types of particles within the same sample for more reliable decision-making:

  • Three FMM channels for three different species of organic particles
  • SIMI channel for extrinsics and inorganic particles

See Clearer With High Magnification

With the high magnification capabilities of the Aura+, you can see more morphological detail of unlabeled particles, enabling decisive discrimination between your lead and undesirable particles.

Quickly differentiate and enumerate cells versus Dynabeads™️, quantify polysorbate degradation, and more.

*Dynabeads refers to the magnetic beads produced by Thermo Fisher Scientific, Inc. Halo Labs is not affiliated with Thermo Fisher Scientific, Inc., and references to Dynabeads or any other third-party trademark do not imply sponsorship, endorsement, or approval.

Key Specifications

Imaging Area 24.6 mm2
Optics 4x and 20x objectives
Minimum volume 5 μL (assay dependent)
Resolution 1.0 pixel/μm
Detectable size range Range from >1 μm (ECD) to <5 mm (ECD)
BMI read time 1 minute/sample
FMM read time 30 seconds/sample
Software Particle VUE 4.x all-in-one software suite (image capture and analysis)

Useful Documents

  • Sprite

    Specification Sheet

Related Documents

  • Sprite

    Aura Family Brochure

  • Sprite

    BMI Tech Note

Ready to bring fast, decisive, low volume particle characterization to all of your biologics development and manufacturing workflows? Get in touch to request a quote.

Frequently Asked Questions

Several methods can be used to count particles, depending on factors such as particle size, type, and concentration. Common techniques include microscopy-based methods (such as light microscopy or electron microscopy), flow cytometry, and Coulter counting. The Halo Labs Aura family also provides particle count data, along with size and identification of particles that can impact drug development. Each method has its advantages and limitations, and the choice depends on the specific characteristics of the particles being counted and the analysis requirements.

Particle count is important in various industries, including pharmaceuticals, food, and environmental monitoring, as it provides crucial information about product quality, cleanliness, and safety. In pharmaceuticals, for example, controlling particle count is essential to ensure product efficacy, stability, and compliance with regulatory standards. Similarly, in food processing, monitoring particle count helps ensure product safety and hygiene. In environmental monitoring, particle count can indicate air or water quality and potential health hazards.


Particle Vue Software

Get particle analysis answers in just a few clicks with flexible, easy-to-use Particle Vue Software.