Overcome Cell Viability Measurement Challenges
Identify Non-Viable and Viable Cells in Your Therapeutic
Aura CL's cell viability assay takes advantage of the increases in plasma membrane permeability observed during apoptosis to accurately identify and measure viable and non-viable cells.
After samples are incubated with a low concentration of a cell viability stain such as DAPI, only non-viable cells can be visualized due to the dye's impermeability. Utilizing Aura CL imaging technology, these labeled non-viable cells can be precisely quantified before applying an increased dose of the same staining agent in order to estimate and determine the amount of viable cell concentrations within each sample—producing results that rival traditional methods such as hemocytometry or flow cytometry.
Simplify Particle ID with FMM
Ensuring product quality and safety is paramount in the manufacturing process. However, using morphology alone to effectively identify particles with different root causes can be unreliable.
This is where FMM comes in. FMM offers an accurate solution by utilizing particle-specific dyes, like Thioflavin T (ThT), that bind to protein aggregates and simplify ID.
With FMM, you are able to easily distinguish between viable cells, non-viable cells, protein aggregates, and more – allowing for a reliable and efficient manufacturing process.