Residual Dynabeads Analysis— Automated, Fast, Easy, and Accurate

Easily and objectively count residual Dynabeads in your cell therapy products with a first-of-its-kind automated solution, giving you better precision and accuracy with higher throughput from the start.

The First Technology to Accurately Detect Residual Dynabeads in Cell Therapies

Why Use Aura to Detect and Count Residual Dynabeads?

  • Best in class Dynabeads identification and quantitation
  • Accurate, fluidics-free cell analysis at high concentrations
  • Obtain detailed information on particles that other methods can’t deliver, including size, morphology, count, and distribution
  • Rapid analysis time of about 1 minute per sample
  • Particles are imaged without the interference of buffer or matrix for higher sensitivity
  • Achieve high sensitivity because particles are imaged without the interference of buffer or matrix
  • Automated data analysis
  • USP 788 Method 2 and USP 1046 compliant
  • Maintain compliance with the option for 21 CFR Part 11 software

Quickly Distinguish Dynabeads from Other Particles

Count Dynabeads with Greater Accuracy and High Throughput

With Aura CL, users have the power to make smart decisions within a crowded cell space.

Unlike other methods that are inefficient and prone to errors, this tool offers greater accuracy and higher-throughput counting capabilities.

And SIMI takes automation one step further with its 'x-ray' vision—allowing it to identify even a single Dynabeads among hundreds of thousands of cells.

LOQ determination for the Dynabeads detection assay.

Particle Vue Software

Get particle analysis answers in just a few clicks with flexible, easy-to-use Particle Vue Software.

Frequently Asked Questions

Dynabeads are small, spherical beads that have been widely used in scientific research and medical applications. Developed by Thermo Fisher Scientific, Dynabeads are composed of a magnetic core and a surface coated with a matrix that specifically binds to various substances, such as proteins, antibodies, or nucleic acids. Due to their unique magnetic properties, Dynabeads can be easily manipulated using a magnetic field. These beads have revolutionized numerous biological techniques by enabling researchers to efficiently isolate, separate, and manipulate specific target molecules from complex mixtures. Their diverse range of applications includes biomarker discovery, immunoprecipitation, cell isolation, and gene expression analysis. Overall, Dynabeads have become invaluable tools in the field of life sciences, enabling researchers to gain deeper insights and advance various areas of study by simplifying and enhancing experimental processes.

Dynabeads typically come in 2.8, 4.5 or 1.0 µm sizes. Most of our customers use 4.5µm beads often referring to them as "5µm beads." 

Typical 5µm Dynabeads sized beads measure as SIMI negative, 5-pixel profiles. For more information, download Tech Note 4.

TN4 Dynabead Analysis V2

Aura can detect any magnetic bead or Dynabeads size 1.0 µm or greater. In the case of Thermofisher Dynabeads offerings, Aura can detect, ID, count and size all of their magnetic bead products. 

Generically speaking, Aura can detect and ID any magnetic beads similar to Dynabeads. Aura can also go beyond magnetics beads, capable of looking for other beads such as polystyrene and even microcarriers.